Reta + HCG Stack Dosing Guide: Running Them Together

Dosing Guide — 2026-11-12

Reta (a triple GLP/GIP/glucagon agonist) and HCG are two of the most common compounds run side by side in metabolic research — Reta drives the weight-loss signaling while HCG is studied for preserving the hormonal axis during aggressive calorie deficits. They're dosed on completely different schedules, so the practical question is how to run both without them colliding. This guide covers the dosing for each, how they share one weekly calendar, and the reconstitution math. For the mechanism rationale, see the Reta + HCG stack research and using HCG with GLP compounds.

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The two schedules at a glance

Compound	Frequency	Standard dose	Reconstitution
Reta	Once weekly	2 mg → 4 mg (titrated)	1 mL (10mg) / 2 mL (20mg)
HCG	2–3× weekly	250–500 IU	2 mL

Reta is the once-a-week anchor; HCG is the mid-week compound dosed two or three times.

Reta dosing (the weekly anchor)

Reta is titrated up slowly to manage nausea. Reconstitute the 10 mg vial with 1 mL bac water (or the 20 mg with 2 mL) — either way 10 units = 1 mg.

Week	Dose	Units
Week 1	2 mg	20 units
Week 2	3 mg	30 units
Week 3+	4 mg	40 units (target)

Hold at 4 mg for weight-loss research; drop to 1 mg (10 units) if nausea flares. Full detail in the Reta dosing guide.

HCG dosing (2–3× weekly)

Reconstitute the HCG 5000iu vial with 2 mL bac water → 10 units = 250 IU, 20 units = 500 IU. The common research dose is 250–500 IU, 2–3× per week. See the HCG peptide dosage guide.

Putting both on one calendar

A clean way to run them so dose days don't stack on top of each other:

Day	Reta	HCG
Monday	—	250–500 IU
Wednesday	—	250–500 IU
Thursday	Weekly dose	—
Saturday	—	250–500 IU (if 3×)

Keep Reta on its own fixed day and slot HCG into the other days. Both are subcutaneous into pinched abdominal fat — rotate sites.

Reconstitution and storage

Reta: refrigerate after mixing, use within ~4 weeks.
HCG: heat-sensitive — refrigerate and use within ~30 days.
One vial of bacteriostatic water covers both reconstitutions.

Important research notes

Reta's appetite suppression can drive muscle loss — keep protein high (≈1 g/lb lean mass) and resistance training in the design. HCG can raise estrogen; hormonal bloodwork is standard when running the two together. For the full stack rationale, see the Reta + HCG stack research.

Disclaimer: All information presented in this article is for educational and informational purposes only. Platinum Biolabs does not promote or endorse the use of peptides for human consumption. All products sold by Platinum Biolabs are intended strictly for laboratory and research use only. Consult a qualified healthcare professional before making any health-related decisions.