Melanotan 2 (MT-2) Dosage Guide: Loading, Maintenance, and Units

Dosing Guide — 2026-11-11

Melanotan 2 (MT-2) is a melanocortin peptide studied for pigmentation (tanning) research. It's dosed in a loading-then-maintenance pattern and run seasonally around UV exposure. This guide covers reconstitution, both protocols in syringe units, cycling, and the safety notes that matter. The numbers match our MT-2 10mg protocol page.

Researcher special: code SAVE25 or PLATINUM25 unlocks 25% off Melanotan 2 (MT-2) 10mg and bacteriostatic water. Every vial ships with a batch-matched COA at 99%+ HPLC purity.

Reconstitution math

Standard reconstitution: add exactly 1 mL bacteriostatic water to the 10 mg vial.

Loading vs maintenance

Start at 250 mcg to assess tolerance — MT-2 commonly causes nausea and flushing early on, which usually fades with continued use.

Administration and cycling

• Route: Subcutaneous, into pinched abdominal fat. Time of day doesn't matter; many dose in the evening since early nausea is easier to sleep through.
• UV still required: MT-2 amplifies the tanning response to UV — it doesn't tan on its own.
• Cycle seasonally: load over 1–2 weeks, maintain 2–3× weekly around sun exposure rather than year-round. The tan fades gradually after stopping; re-load briefly next season.

Safety notes (important)

• Nausea and facial flushing — most common in the first few days.
• Appetite suppression.
• Mole/freckle darkening — MT-2 darkens existing moles and freckles and can create new ones. Get a skin check before and during use if you have many moles or a family history of skin cancer, and have any changing/atypical moles evaluated by a dermatologist.
• Spontaneous erections in men (MT-2 is closely related to PT-141).

For the melanocortin background, see the PT-141 melanocortin research overview. Refrigerate after reconstitution and use within 4 weeks.

Disclaimer: All information presented in this article is for educational and informational purposes only. Platinum Biolabs does not promote or endorse the use of peptides for human consumption. All products sold by Platinum Biolabs are intended strictly for laboratory and research use only. Consult a qualified healthcare professional before making any health-related decisions.