Semax Dosage Guide: Injection and Nasal Spray Protocols

Dosing Guide — 2026-11-10

Semax is a nootropic peptide studied for cognition, focus, and neuroprotection. It can be dosed by subcutaneous injection or — more commonly for cognitive research — as a nasal spray. This guide covers both routes, morning timing, and the common 5-on-2-off cycling pattern. The numbers match our Semax 10mg and Semax spray protocol pages.

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Semax 10mg vial

Standard reconstitution: add exactly 2 mL bacteriostatic water.

MetricValue
Peptide10 mg
Bac water2 mL
Concentration5 mg/mL
Per 10 units500 mcg

Dose: 500 mcg daily (10 units), in the morning.

Semax nasal spray (no mixing)

The spray is pre-mixed — each spray delivers ~50 mcg.

LevelDoseSprays
Conservative100 mcg1 spray per nostril, once daily AM
Best results200 mcg2 sprays per nostril AM (and again in the afternoon if desired)

Prime the pump before first use, then refrigerate.

Timing and route

Cycling

ParameterValue
Cycle length1–2 months common
Time off2–4 weeks
5-on / 2-offVery common — reduces overstimulation and diminishing effects over time

Related nootropics

Semax is often discussed alongside Selank (the calmer, anxiolytic counterpart). See the Semax research overview, Selank research, and can peptides help with brain fog. Refrigerate the reconstituted vial and use within 4 weeks; keep the spray refrigerated and use within the timeframe on the bottle.

Disclaimer: All information presented in this article is for educational and informational purposes only. Platinum Biolabs does not promote or endorse the use of peptides for human consumption. All products sold by Platinum Biolabs are intended strictly for laboratory and research use only. Consult a qualified healthcare professional before making any health-related decisions.

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