How to Use the Shredder Stack: A Step-by-Step Research Protocol

Stacks — 2026-06-12

The Shredder Stack pairs three compounds that each work on a different part of body composition: Reta drives the energy deficit, Tesamorelin protects lean mass, and MOTS-C shifts how cells burn fuel. Run together, they cover every major lever at once. This guide walks through exactly how researchers set the stack up and run a one-month protocol.

This article is educational and for research context only. Platinum Biolabs sells these compounds for laboratory use and does not endorse human consumption.

What's in the Stack

The base Shredder Stack contains one vial of each — enough Tesamorelin and MOTS-C for only about 10 days. The Shredder Stack Complete adds extra Tesamorelin and MOTS-C (3× each) so one purchase carries a full month of all three.

What You'll Need

Step 1: Reconstitute Each Vial Separately

Never mix compounds in a single vial. Reconstitute each on its own:

VialBac waterConcentrationUnit math
Reta 20mg2 mL10 mg/mL10 units = 1 mg
Tesa 10mg1 mL10 mg/mL10 units = 1 mg
MOTS-C 10mg1 mL10 mg/mL40 units = 4 mg

Inject the bac water slowly down the inside wall of each vial — don't squirt it onto the powder — then swirl gently until clear. Don't shake. Refrigerate all three after mixing and use within four weeks.

Step 2: Run the Weekly Schedule

The three compounds sit on different cadences, so the simplest approach is a fixed weekly layout:

Step 3: Titrate the Reta

Reta is the only compound you titrate. Start low and step up:

Most protocols hold at 4 mg. Only step toward 6–8 mg if results stall after six to eight weeks, and only one step at a time. Tesamorelin and MOTS-C are not titrated — they run at a flat dose from day one (Tesa 1 mg nightly, MOTS-C 4 mg twice weekly).

Step 4: Track the Right Things

Weight alone is noisy. Researchers usually log:

Step 5: Taper, Don't Stop Cold

At the end of a cycle, taper Reta down rather than quitting abruptly — that limits rebound appetite. Tesamorelin and MOTS-C can simply be stopped. Many researchers keep Reta at a 1–2 mg/week maintenance dose afterward.

Where the Bundles Fit

The base Shredder Stack holds one vial of each — only about 10 days of Tesamorelin and MOTS-C (one Reta vial runs ~5 weeks on its own), so the full three-compound effect is short before you're on Reta alone. The Shredder Stack Complete holds 3× Tesa and 3× MOTS-C — a full month of all three running together. Since the stack lasts about a month, sustained protocols re-order month over month. A full dosing reference for the stack lives on the dosing guide.

When you're ready to source matched-batch material, the 25% researcher discount applies to the stack and the individual vials. Every vial ships with a COA and 99%+ HPLC purity verification.

Disclaimer: All information presented in this article is for educational and informational purposes only. Platinum Biolabs does not promote or endorse the use of peptides for human consumption. All products sold by Platinum Biolabs are intended strictly for laboratory and research use only. Consult a qualified healthcare professional before making any health-related decisions.

Shop Research Peptides