Triz (Tirzepatide) Dosage Guide: Weekly Titration and Units (10mg & 30mg)

Dosing Guide — 2026-11-11

Triz (tirzepatide) is a dual GLP-1 / GIP receptor agonist studied for metabolic and weight-loss research. Like other GLP compounds, it's dosed once weekly on a slow titration. This guide covers reconstitution and the full titration in syringe units for both the Triz 10mg and 30mg vials. The numbers match our Triz 10mg and Triz 30mg protocol pages.

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Reconstitution math

Vial	Bac water	Concentration	Per 10 units
Triz 10mg	1 mL	10 mg/mL	1 mg
Triz 30mg	3 mL	10 mg/mL	1 mg

Both end up at 10 mg/mL (10 units = 1 mg), so the unit math is identical — the 30mg vial just lasts 3× longer.

Weekly titration schedule

Hold each step ≥4 weeks before moving up. Many researchers plateau effectively at 5–7.5 mg.

Step	Dose	Units (U-100)
Onboarding	2.5 mg	25 units
Step up	5 mg	50 units
Step up	7.5 mg	75 units
Target (if needed)	10 mg	100 units

Administration and cycling

Route: Subcutaneous, once per week, same day each week.
Cycle: 3–12+ months common; maintenance or taper rather than classic cycling. Hold an extra 1–2 weeks at a step if side effects are intense.

Side effects and support

Nausea after titration steps (titrate slowly).
Muscle loss risk — protein (≈1 g/lb lean mass) + resistance training.
Occasional diarrhea, fatigue; constipation is common (fiber supplement helps).

Triz vs other GLP compounds

Triz is the dual GLP-1/GIP agonist — a step up from single-agonist Sema and a step below triple-agonist Reta. See Triz vs Sema, Reta vs Triz, and the Triz dual-agonist research overview. Refrigerate after reconstitution and use within 4 weeks.

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