MOTS-C 10mg Dosage Guide: Reconstitution and Dosing

Dosing Guide — 2026-11-07

MOTS-C is a mitochondrial-derived peptide studied as an exercise mimetic and metabolic regulator. This guide covers the practical dosing of the MOTS-C 10mg vial — reconstitution math, the two most common protocols (conservative daily and experienced twice-weekly), and vial longevity. The numbers match our MOTS-C 10mg protocol page. For the science behind the peptide, see MOTS-C: the mitochondrial peptide.

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Reconstitution math

Standard reconstitution: add exactly 1 mL bacteriostatic water to the 10 mg vial.

Metric	Value
Peptide	10 mg
Bac water	1 mL
Concentration	10 mg/mL
Per 10 units (U-100 syringe)	1 mg
Per 50 units	5 mg

So on a U-100 insulin syringe, 10 units = 1 mg and 50 units = 5 mg.

The two common protocols

Conservative — daily - 1 mg (10 units) once daily - A gentle way to assess tolerance - One 10 mg vial lasts ~10 days at this rate

Experienced — twice weekly (increasingly favored) - 5 mg (50 units) twice weekly — e.g. Monday and Thursday - One 10 mg vial = ~1 week (2 doses) — plan on ~4 vials for a full month - Pulsed twice-weekly dosing is increasingly preferred in metabolic and mitochondrial research over daily dosing

Unit cheat sheet (MOTS-C 10mg in 1 mL) | Units | Volume | Dose | |-------|--------|------| | 10 units | 0.10 mL | 1 mg | | 20 units | 0.20 mL | 2 mg | | 50 units | 0.50 mL | 5 mg |

Administration

Route: Subcutaneous, into the fatty layer under pinched abdominal skin.
Timing: Morning or pre-workout aligns with the energy-mimetic effect.
Rotate injection sites.

Cycling

Parameter	Typical
Cycle length	4–8 weeks
Time off	2–4 weeks

Vial longevity summary

Protocol	Dose	Days per 10mg vial
Conservative daily	1 mg (10 units)	~10 days
Experienced 2×/week	5 mg (50 units)	~1 week (2 doses) — ~4 vials/month

Storage

Refrigerate after reconstitution and use within 4 weeks. Keep lyophilized (unmixed) vials refrigerated and protected from light. Full technique is in the reconstitution guide.

For how MOTS-C is studied in fat-loss and metabolic contexts, see MOTS-C for weight loss research.

Disclaimer: All information presented in this article is for educational and informational purposes only. Platinum Biolabs does not promote or endorse the use of peptides for human consumption. All products sold by Platinum Biolabs are intended strictly for laboratory and research use only. Consult a qualified healthcare professional before making any health-related decisions.